However, the ratio of CD3+CD4+CD69+ T/CD3+CD8+CD69+ T was significantly lower in the G- sepsis subgroup than that in the G+ sepsis subgroup (0.27(0.15, 0.50) vs. 0.92(0.33,1.73), P<0.001) (Figure 2B), although the percentage of CD3+CD4+CD69+ T cells was lower in the G- sepsis subgroup than that in the G+ sepsis subgroup, while no significant difference was found (0.60(0.42,0.84) vs. 0.91 (0.42,1.18), P=0.204) (Table 4). The gene discussed is CD8A; the disease is Sepsis.