CD8A and bacterial infectious disease with sepsis: The correlation of ICU stay with CD3+CD69+T subsets was firstly analyzed, and it was found that ICU stay was positively correlated with CD3+CD69+T (r=0.3017, P=0.0416) and CD3+CD8+CD69+T subsets (r=0.3919, P=0.0071), and negatively associated with the ratio of CD3+CD4+CD69+ T/CD3+CD8+CD69+ T (r=-0.3916, P=0.0071) in patients with G- bacterial sepsis, while did not significantly correlate with CD3+CD4+CD69+T subsets (Figure 4A).