The low level of CD3+CD4+CD69+T/CD3+CD8+CD69+T ratio in G- sepsis (versus G+ sepsis) was mainly due to the upregulated CD3+CD8+CD69+ T (%) (CD8+T cell activation) and in part a consequence of the relatively loss of CD4+T(%)(CD4+T suppression). Here, CD4 is linked to Sepsis.