In G- sepsis (versus G+ sepsis), we observed that both CD3+CD69+T and CD3+CD8+CD69+T (%) were remarkably upregulated, while CD4+T/CD8+T ratio, CD3+CD4+CD69+T (%) and CD3+CD4+T were downregulated (although the latter two indexes without significant difference). The gene discussed is CD4; the disease is Sepsis.