CD4 and infection: Although the platelet count was not significantly different between sepsis group and no infection group, or between G- sepsis and G+ sepsis (Supplementary Figure S4A), however, the platelet count was negatively correlated with CD3+CD69+T(%) and CD3+CD8+CD69+T(%) and positively correlated with CD3+CD4+CD69+T/CD3+CD8+CD69+ T, in bacterial sepsis group (n=66) (Supplementary Figure S4B) and G- sepsis (n=46)(Supplementary Figure S4C), but not in G+ sepsis group (n=20) (Supplementary Figure S4D).