The T lymphocyte subset analysis revealed that patients in the bacterial sepsis group had higher percentages of CD3+CD38+ T cells (13.74 (8.06,24.07) vs. 8.62 (6.23,12.90)) and CD3+CD69+ T cells ((3.60 (1.96,5.04) vs. 1.46(0.83,2.29)) than those in the no infection group, and further test indicated that percentages of CD3+CD8+CD38+ T, CD3+CD8+CD69+ T, and CD3+CD4+CD69+ T subsets were higher in the bacterial sepsis group than in the no infection group (Table 4). The gene discussed is CD8A; the disease is bacterial infectious disease with sepsis.