Genomic sequencing test showed no driver mutation for targeted therapy (ALK(−), BRAF(−), BRCA1(−), BRCA2(−), EGFR(−), ERBB2(HER2)(−), FGFR2(−), FGFR3(−), KIT(−), KRAS(−), MET(−), NRAS(−), NTRK1(−), NTRK2 (–), NTRK3(−), PDGFRA(−), RET(−), ROS1(−), and IDH2(+)); however, the patient tested positive for PD-L1 (TPS=25%, IPS<1%, tested using a Ventana SP263 assay), with tumor mutation burden of 7.26 Muts/Mb (tested using a next-generation sequencing (NGS) panel and paired with peripheral blood sample sequencing). The gene discussed is CD274; the disease is neoplasm.