Supplementation of n-3 polyunsaturated fatty acids (n-3 PUFAs) to pup rats from postnatal week three to week 13 was revealed to increase Nrg4 and UCP1 mRNA levels in adipose tissue and improve NAFLD (Yang et al., 2021). The gene discussed is NRG4; the disease is metabolic dysfunction-associated steatotic liver disease.