A previous study reported that PCNP had an inhibitory role in neuroblastoma cell processes such as growth, migration and invasion through increased ratios of Bad/Bcl-xl and Bax/Bcl2 and upregulation of Caspase-3, 8, and 9 (11), in which the PI3K/AKT/mTOR signaling cascade also played a crucial role. The gene discussed is BCL2; the disease is neuroblastoma.