CCR7 and neoplasm: In addition, our study revealed that MXRA8 expression correlated with the expression of multiple metastasis-associated chemokines (CXCL12, CXCL13, CCL9, CCL21, CXCR4, CXCR5, and CCR7) (31–37), suggesting that MXRA8 may be involved in tumor invasion and metastasis by regulating the secretion of chemokines.