In addition, our study revealed that MXRA8 expression correlated with the expression of multiple metastasis-associated chemokines (CXCL12, CXCL13, CCL9, CCL21, CXCR4, CXCR5, and CCR7) (31–37), suggesting that MXRA8 may be involved in tumor invasion and metastasis by regulating the secretion of chemokines. Here, CXCL12 is linked to neoplasm.