By decreasing the expression of CHOP and activating caspase-12, it has been shown that activating VDR limits the expression of ERS-relative protein, thereby alleviating myocardial ischemia/reperfusion injury (Pu et al., 2013; Yao et al., 2015; Haas et al., 2016). Here, VDR is linked to myocardial ischemia.