OCLN and pulmonary arterial hypertension: Of 33 antibodies to neural and tight junction proteins, actin immunoglobulin G (IgG), occludin/zonulin (OZ) immunoglobulin A (IgA), OZ IgG, myelin oligodendrocyte glycoprotein (MOG) IgG, MOG immunoglobulin M (IgM), myelin basic protein (MBP) IgA, MBP IgG, astrocytic protein (S-100) IgG, S-100 IgM and cerebellar antigen (CEREB) IgG in serum, and MBP antibodies in CSF were higher in children exposed to high levels of PAH compared to controls (58).