Based on UALCAN analysis,[17] the mRNA and protein expressions of TFRC from The Cancer Genome Atlas (TCGA) and the Clinical Proteomic Tumor Analysis Consortium (CPTAC) datasets are increased in all stages of colon tumors as compared to normal colons (Figure S1C–S1F, Supporting Information), indicating that TFRC upregulation is an early event during colon tumorigenesis. The gene discussed is TFRC; the disease is colonic neoplasm.