CD4 and neoplasm: In line with the TCR repertoire results, scant CD4+ (68 cells·mm−2) and CD8+ (37 cells·mm−2) T‐cells within the tumor island or in the stroma and PD‐L1 were negative (< 1%) in all four LP tumors (Fig. 4G), further suggesting the immune‐cold microenvironment with limited and heterogeneous T‐cell infiltration in the four LP tumors.