β-catenin mRNA was positively correlated with mRNAs of IRP2 and TfR1 in 1406 cancer cell lines (Fig. 4O, Additional file 1: Fig. S3A) and β-catenin-frequently activated human HCC, COAD and UCEC samples (Fig. 4P, Additional file 1: Fig. S3B). The gene discussed is IREB2; the disease is cancer.