We next tested in zebrafish at 8 dpf if the Cxcl12/Cxcr4 system is similarly involved in the behavioral changes induced by embryonic ethanol exposure, measuring both locomotor activity (distance traveled) and the anxiety-like behaviors of thigmotaxis (% time in outside zone) and light-preference (% time in light zone). The gene discussed is CXCR4; the disease is Anxiety.