Modulation of cellular miR-130b levels has led to regulation of several pro-oncogenic pathways, including NF-κb activation in bladder cancer [40], angiogenesis and EMT in colorectal carcinoma [35], as well as enhanced proliferation and invasion of glioma cells [41, 42] and hepatocellular carcinoma [43]. This evidence concerns the gene NFKB1 and central nervous system cancer.