DUST (p16/Ki-67 dual staining technology) could be a better cervical cancer screening method in WLHIV in resource-limited settings due to its better sensitivity (91.9–97.2%) and specificity (82.1–95.2%) in detecting CIN2/3 lesions when compared to the currently available screening tests such as Pap smear, HPV DNA and VIA testing [23–27]. This evidence concerns the gene MKI67 and cervical cancer.