Existing literature demonstrates the utility of albumin levels in predicting outcomes after orthopaedic surgery.27, 28, 29, 30 Kishawi et al28 found that patients undergoing total joint arthroplasty with low albumin levels were at markedly increased risk of infection, pneumonia, sepsis, myocardial infarction, and other adverse outcomes compared with patients with normal albumin levels. The gene discussed is ALB; the disease is infection.