Additionally, BMI-SDS significantly increased by diabetes duration in female participants only (mean ± SD: <2 years 0.39 ± 0.05; 2–5 years 0.49 ± 0.04; and >5 years 0.60 ± 0.04; p<0.0001) and BMI-SDS increased more during insulin therapy (0.44 vs 0.18, p<0.0001) [23, 29]. Here, INS is linked to diabetes mellitus.