NBEAL2 and systemic lupus erythematosus: After GpS treatment, the expression levels of anti-DS-DNA antisubstance and ANA in serum of mice decreased significantly (P < 0.05), this phenomenon suggests that GpS, as a natural plant component, can reduce the production of autoantibodies and slow the progression of SLE, and it is likely to become a new drug for the prevention and remission of SLE (Figure 7).