On the other hand, the rats in the MI/RI + Sevo group exhibited increased LVEF% and LVFS% (Figure 1a, p < 0.05), normal myocardial fiber arrangement, alleviated cardiomyocyte interstitial edema, and quenched inflammatory cell infiltration (Figure 1b, p < 0.05), declined myocardial infarction area (Figure 1c, p < 0.05), in conjunction with decreased levels of CK-MB, cTnI and serum LDH levels (Figure 1d, p < 0.05). The gene discussed is TNNI3; the disease is myocardial infarction.