HHEX and infection: Immunofluorescence confirmed no expression of c-myc–tagged protein in left carotid arteries from mice infected with Ad: Control 7 days after infection, while c-myc–tagged PRH S163C:S177C protein was observed within the nuclei of cells within left carotid arteries 7 days post ligation infected with Ad: PRH S163C:S177C (Figure 3A and 3B), After 28 days, a significant reduction in intimal thickening in carotid arteries infected with Ad: PRH S163C:S177C with respect to the empty vector was observed (Figure 3C through 3F).