According to previous studies in other fields, miR-3202 can promote endothelial cell apoptosis through FAIM (45); miR-4516 inhibits liver cancer cell proliferation and progression through SOX5 (46); miR-4476 could promote glioma progression through APC/β-catenin in the Wnt pathway (47). The gene discussed is SOX5; the disease is central nervous system cancer.