CD40LG and hematopoietic and lymphoid cell neoplasm: Hematologic cancer patients segregated based on a major cluster of high production of immune mediators in the Severe-Death group, together with lower levels of IgG and IgM anti-SARS-CoV-2 proteins and lower counts of leukocyte subpopulations (Figure 5A). The solid tumor groups separated the Severe-Death patients in one branch characterized by higher production of soluble immune factors and lower production of IgM.