Moreover, β2GPI is naturally present on neutrophils, more than on monocytes, both in APS patients and healthy controls, and neutrophil extracellular traps (NETs) have been recently shown to contribute to the coagulation cascade and to be an integral component of arterial and venous thrombi with different etiology, including APS clots (13–15). The gene discussed is APOH; the disease is autoimmune polyendocrinopathy.