ASXL3 and severe feeding difficulties-failure to thrive-microcephaly due to ASXL3 deficiency syndrome: Bainbridge-Ropers syndrome (BRPS) or additional sex combs-like 3 (ASXL3)-related disorder is a neurodevelopmental disorder caused by a de novo truncating or missense mutation in the ASXL3 gene found on chromosome 18q12.1 [1-4].