IL6 and thalassemia: Findings in poly-transfused patients with thalassemia major demonstrated that serum levels of IL-6 are undetectable or within the normal range (Lombardi et al., 1994), whereas other results showed an increase in the circulating levels of this cytokine in the same category of patients (Oztürk et al., 2001; Aggeli et al., 2005; Moshtaghi-Kashanian et al., 2006; El-Rasheidy et al., 2016).