With an extensive test battery in the domains of motor function, social and repetitive behavior, anxiety and avoidance behavior, and cognition, the Shank3Δ11 mouse model, also denominated below as Shank3 KO, was characterized in this study at two time points resembling periods in human adolescence and early adulthood (Dutta and Sengupta, 2016). This evidence concerns the gene SHANK3 and Anxiety.