Albumin, as a negative acute phase protein and a nutritional marker, has an influence on the development of atherosclerosis and unfavorable cardiovascular events, such as NR.9 Further, hypoalbuminemia was found to be a predictor of poor outcomes in patients with ACS by Polat et al.20 Additionally, lower levels of albumin on admission, even in the normal range, were a predictor of death in ACS individuals.21 In contrast to these findings, our multivariate model found that neither CRP nor albumin were associated to the formation NR in this investigation. This evidence concerns the gene CRP and atherosclerosis.