AKT1 and laryngeal carcinoma: A case in point is that the active component of Alpiniae officinarum Rhizoma, galangin, can inhibit the proliferation of human laryngeal cancer cell lines (tu212, m4e, and Hep-2) while causing no toxic effects to normal cells (HBE, hhl-5, and RTE) through p38 and Akt/NF-κB/mTOR pathway, exhibiting great anti-laryngeal cancer effects and security (Wang and Tang, 2017).