ACP5 and osteoporosis: In addition, biochemical markers of bone turnover, including bone formation markers and bone resorption markers, are also an important basis for the clinical diagnosis of osteoporosis, such as alkaline phosphatase (ALP), osteocalcin, tartrate-resistant acid phosphatase (TRACP), and serum C-terminal telopeptide of type 1 collagen (S-CTX).