Ortega and Bahramrezaie et al. illustrated that RVT improved irregular angiogenesis by reducing the expression of VEGF mRNA, VEGF protein, and the intermediate factor HIF1 to improve disorders of ovulation, subfertility, and endometriosis caused by ovarian hyperstimulation syndrome (Ortega et al., 2012b; Bahramrezaie et al., 2019). Here, VEGFA is linked to endometriosis.