NFKB1 and Fabry disease: It was found that NF-κB expression was elevated in gastric smooth muscle cells of model FD rats, and after drug intervention with Chaihushugan Powder, NF-κB expression was significantly reduced in FD rats, indicating that Chaihushugan Powder could inhibit excessive apoptosis of gastric smooth muscle tissue cells by inhibiting the activation of NF-κB signaling pathway in order to promote gastric motility and improve FD symptoms (Shang, 2017).