After Chaihushugan Powder intervened in FD rats, p-elF2αexpression was reduced, indicating that elF2α phosphorylation was inhibited, from which it can be deduced that Chaihushugan Powder has an inhibitory effect on the PERK/elF2αpathway, suppressing endoplasmic reticulum stress and promoting gastric motility (Zhou, 2018). This evidence concerns the gene EIF2AK3 and Fabry disease.