Li showed that the expression of CRF in the gastric sinus of FD rats was higher than that of the normal group, and the expression of urocortin 2 (UCN2) was lower than that of the normal group, and Xiangsha Liujunzi Decoction could reduce the level of CRF in the gastric sinus of FD rats with spleen deficiency, and the effect was more significant at higher doses, which could increase the expression of UCN2 mRNA and protein, improve gastric emptying rate and promote gastric motility (Li et al., 2022b). The gene discussed is UCN2; the disease is Fabry disease.