Compared with survivors, deceased patients at 2 years were older, had a higher incidence of severe renal failure, chronic pneumopathy, HFrEF, and PHT, had a wider vena contracta, had a lower RV-PA coupling ratio (TAPSE/PASP), were more likely to have ACHD and had higher serum creatinine and NT-proBNP levels (Table 3). This evidence concerns the gene NPPB and acute kidney injury.