Hence, aim of the current study was to examine the possible association between eight SNPs in oxidative stress-related genes, namely rs4880 (SOD2), rs1001179 (CAT), rs1050450 (GPX1), rs1695 (GSTP1), rs1138272 (GSTP1), rs1799983 (NOS3), rs6721961 (NFE2L2), and rs660339 (UCP2), and the susceptibility to develop migraine and sub-clinical phenotypes, in South-eastern European Caucasian (SEC) clinically examined patients and controls (Table 1, Figure 1). Here, UCP2 is linked to migraine disorder.