In 1,4-dihydroxy quininib treated UM explants, a significant negative correlation was observed between IL-13 secretion and tumour thickness; IL-1β secretion and tumour dimensions (LUD and LUH); IL-8 secretion and tumour dimensions; and TNF-α secretion and LUH (Figures 3B–D). This evidence concerns the gene IL1B and neoplasm.