In the immunoblotting assay, serum samples from autoAbs-positive AOSD patients could also more effectively suppress the STAT1 phosphorylation on THP-1 cells (56.70±34.79%), particularly the samples from two patients (P1 and P2) with high-titer anti-IFN-γ autoAbs (22.61 and 16.91%, respectively), compared to samples from HC (104.3 ± 29.51%, p = 0.057) (Figures 2E, F). This evidence concerns the gene IFNG and adult-onset Still disease.