TGFB1 and Hepatic fibrosis: To investigate the repairment function of hADMSCs-Exo on fibrosis, we designed both in vitro and in vivo experiments as illustrated in Fig. 2A. Considering that TGF-β1-regulated hepatic stellate cells (HSCs) are responsible for liver fibrosis, we constructed the fibrotic cell model by treating LX-2 cells with TGF-β1.