Nine independent significant SNPs (P value < 2e− 5 and LD r2 < 0.5) were identified in the GWAS, among which rs7754840 in the intron regions of the CDKAL1 gene and rs10830962 located upstream of the MTNR1B gene showed the strongest association with GDM. The gene discussed is MTNR1B; the disease is gestational diabetes.