PDE5A and Nasal congestion: PDE5 medications were associated with the greatest proportion of side effects for flushing of the skin (n = 61, 51.2%), headache/dizziness (n = 34, 28.6%), nasal congestion (n = 47, 39.5%), nausea (n = 32, 26.9%), heartburn (n = 32, 26.9%), difficulty sleeping (n = 24, 20.2%) and nose bleeds (n= 26, 21.8%), which was similar to what has been reported elsewhere [21].