The nanobots were prepared by fabricating a hemispherical shell of Fe3O4 on Mg nanoparticles and then by selectively assembling multiple components viz; (i) anti-Epithelial cell adhesion molecule (EpCAM) monoclonal antibody (Ab)/transferrin (Tf) for targeting cancer cells, (ii) cyanine 5 NHS (Cy5) dye for particle labeling, (iii) fourth generation (G4) dendrimer for multiple conjugation and (iv) glutathione (GSH) linker by chemical conjugation onto one side of Mg nanoparticle using the parafilm method. This evidence concerns the gene TF and cancer.