Factors traditionally associated with a high risk of recurrent disease include histologic subtype, FIGO G3 histology, myometrial invasion ≥50%, LVSI,25, 26, 27 L1 cell adhesion molecule expression,28,29 lymph node metastases and tumour diameter >2 cm. This evidence concerns the gene L1CAM and metastatic malignant neoplasm in the lymph nodes.