GPT and Hyperammonemia: Furthermore, in-vitro and in-vivo studies delineated the ability of resveratrol to improve liver functions represented by declination in ALT and AST levels, reduction of ammonia levels, maintenance of the blood-brain barrier (BBB) integrity, amelioration of hyperammonemia-induced mitochondrial dysfunction, and disruption in the glutamatergic system and cellular redox imbalance (Bobermin et al. 2015, 2018; Vairappan et al. 2019).