Results from MOG–EAE were compared to those obtained from PLP–EAE mice, a model of relapsing–remitting MS mainly characterized by spinal neuroinflammation and a lower degree of axonal loss that showed no significant modification of MBP (Fig. 2G), GAP43 (Fig. 2H), and neurofilament H (Fig. 2I) protein expression. Here, PLP1 is linked to myeloid sarcoma.