Moreover,high PU.1 expression positively correlates with the number of activated CD4memory T cells, resting NK cells, M2 macrophages, resting dendritic cells, andneutrophils in the tumor stroma [15].Our study failed to reveal any prognostic significance of this protein, butconsistent with the literature data, we observed a positive correlation of thePU.1+ cell content with macrophages and B-cells, as well as PD-L1+ cells in thetumor stroma. Here, SPI1 is linked to neoplasm.