CK levels are very high (50–100 times) in SINAM, and the large amounts of myoglobin released from the muscle enter the circulation and get filtered in the glomerulus to be deposited in the renal tubules, which can result in acute kidney injury.58 As SINAM is an antibody-mediated process, it differs from other SRMs, as symptoms may occur months after stopping statin therapy. Here, MB is linked to acute kidney injury.