HAVCR1 and acute kidney injury: In past, KIM-1 along with two other markers was studied in HIV associated pre-eclampsia women and was found significantly raised in this population when compared with normal pregnancies.16 A meta-analysis has revealed significant superiority of KIM-1 in early detection of AKI, well before rise in serum creatinine, with summary receiver operating curves (sROC) showing an area under the curve of 0.86.10 This meta-analysis also highlights heterogeneity in KIM-1 levels with age, population setting and time of measurement of KIM-1.