The rise in urinary NGAL levels is reported to be directly related to the severity of AKI.4 The rise in NGAL is seen before the rise in serum creatinine levels, and hence is considered a marker of acute ischemic injury to the kidney has been identified in emergency room settings, after cardiac surgery and after chemotherapy.4,5 In a case-control study comparing healthy women with pre-eclampsia women, urinary NGAL, showed a significant rise in women with eclampsia, but not with pre-eclampsia (PET).6 Here, LCN2 is linked to acute kidney injury.