In this particular study serum creatinine remained more sensitive and specific in patients developing AKI after contrast induced injury, though levels of KIM-1 were high in pre-contrast and post contrast samples.17 A meta-analysis performed for role of IL-18 in prediction of AKI via sROC analysis has revealed a pooled diagnostic OR of 5.11 and estimated area under the curve of mean ROC was 0.77. The gene discussed is IL18; the disease is acute kidney injury.