MME and neoplasm: CD10 was demonstrated to be associated with higher tumor grade in UBC,10-12 as well as higher tumor stage10 and lymph node metastasis.2 Some studies did not find an association between CD10 immunoexpression and tumor stage,11 tumor grade,2, muscle invasion2, lymph node metastasis,2 or vascular space invasion.2 In contrast, Bircan et al.13 found that CD10 was inversely correlated with tumor invasiveness and pathological stage.