As the association of ALDH1A1 and ALDH7A1 with PCa progression has been definitively demonstrated,102, 138 it is proposed that high levels of ALDH3A1, ALDH1A1, and ALDH7A1 are involved in prostate tumorigenesis, though the detailed contribution of them to PCa requires further investigation. The gene discussed is ALDH7A1; the disease is posterior cortical atrophy.