CD8A and neoplasm: For the non-tumor area, the mean number of infiltrating CD8+ T cells per mm2 in responders was 5.1-fold higher than in non-responders (82.7 ± 170.5 vs. 16.1 ± 17.3); however, this difference was not statistically significant (p = 0.43) because the median of responders and non-responders was similar (6.45 vs. 9.97) (Fig. 4A).