While an independent role in cancer initiation is weak, Pim kinases show especially strong synergistic roles in the presence of other oncogenes, such as c-Myc/n-Myc (C/N-MYC Proto-Oncogene), and Bcl-2 (BCL2 Apoptosis Regulator) and in the presence of various carcinogens to initiate cancer [10]. Here, MYCN is linked to cancer.