We confirmed that, for basal subtype breast cancer, CCL1 (95%CI: 0.00–0.50, p = 0.022) and MYH6 (95%CI: 0.00–0.61, p = 0.026) were independent protective factors while IFNK (95%CI: 7.05–1482.33, p < 0.001) and SOAT2 (95%CI: 4.42–1184.82, p = 0.003) were an independent risk factor in a training set with Cox regression analysis and survival analyses with the four genes mentioned above (Fig.  6 & 7 A-D). Here, SOAT2 is linked to breast cancer.