POSTN and asthma: In the multivariate analysis, adjusting for potential confounders (maternal atopy, parental asthma, atopic dermatitis, prematurity, RSV infection, and cigarette smoke exposure), the results showed a lower risk of asthma at 4 years of age in those infants with positive periostin detection at admission for bronchiolitis, independently of their atopic status (aOR: 0.511 CI 95% 0.284–0.918, p: 0.025) (Table 4).