Concerning the medium-term respiratory evolution, the levels of nasal periostin tended to be higher in those infants who did not develop recurrent wheezing (p = 0.06), never needed respiratory admissions (p = 0.02), never received inhaled bronchodilators (p = 0.02) or oral corticosteroids (p = 0.03), were not prescribed chronic maintenance treatment for asthma (p = 0.002) and did not report current asthma (p = 0.004) (Fig. 2). The gene discussed is POSTN; the disease is asthma.