Additionally, for the further classification of an ALS cerebellum sample as C9orf72-ALS or sporadic ALS by the classifiers trained on LASSO-selected genes, HOXC10 was identified as the second most determinative gene (ranked immediately after C9orf72) (Additional file 1: Table S4). The gene discussed is HOXC10; the disease is amyotrophic lateral sclerosis.