Further supporting a pro-proliferative role for NRBP1 in breast cancer, data extracted from the Dependency Map (DepMap) portal indicated that NRBP1 is a breast cancer context-specific fitness gene required for the efficient proliferation of multiple breast cancer cell lines, including the TNBC lines MDA-MB-231, CAL51, HCC-1954 and MDA-MB-436 (Fig. 3D) [12]. The gene discussed is NRBP1; the disease is hepatocellular carcinoma.